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No matter how much one wants to or tries, as in I couldn't eat another bite, not with the best will in the world. [Mid-1800s]
American Heritage Idioms
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general::
Phrase(s): with the best will in the world
however much one wishes to do something or however hard one tries to do something. • With the best will in the world, Jack won’t be able to help Mary get the job. • With the best will in the world, they won’t finish the job in time.
McGrawhill's American Idioms And Phrasal Verbs